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Bacilligen Inc

9430 Key West Highway, Suite 120
Rockville, MD, USA

Category: Drug Delivery

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Maryland Biotech Industry Map

Bacilligen Inc is a biotechnology company engaged in developing vaccines for infectious diseases and technology for biological manufacturing. The company was founded in 2006.

Bacilligen's technologies include: BVS (Bacilligen Vector System/Vaccines) and rMB - Recombinant Mycobacteria/Bladder Cancer. Although based upon bacteriophage (viruses that infect bacteria), the BVS capsids can enter human/mammalian cells where their double-stranded RNA cargo is delivered and expressed to produce proteins (or therapeutic RNA). The company's BVS possesses the utility of mammalian-derived and generated vectors such as adeno-associated virus or adenovirus since it can enter human cells. Its proprietary rMB technology equips the Mycobacteria to more fight cancer cells, and resist interfering (pre-existing) immunity. The company has created rMB product candidates based on the proprietary genetic manipulations it has introduced into strains of Mycobacteria.

Bacilligen entered into a collaborative research and development agreement with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) to develop a single BVS vaccine against anthrax and plague. The company is funded via two NIH grants to develop BVS-based vaccines for HIV and flu.