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9600 Medical Center Drive
Rockville, MD 20850, USA

Category: Analytical Services (CRO); Research Services & Supplies; Testing Services

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Maryland Biotech Industry Map

BIOQUAL, Inc. is committed to providing quality research, development and consulting services to Government and commercial contract clients. The company was founded by John C. Landon in 1981.

BIOQUAL laboratory offers services used to evaluate immunologic, virologic and molecular biologic parameters in animal models and support the development of vaccines and therapeutics for infectious diseases in humans. Its laboratories are actively involved in the evaluation of vaccines, vaccine therapeutics, microbicides and drug therapies in animal models including non-human primate models of infectious diseases in humans. Biological evaluation in these models may be performed by a variety of methods, including quantitative PCR, virus-cultivation assays, antigen and antibody ELISA detection assays, lymphocyte proliferation, intracellular cytokines, GLP Studies and flow cytometry.

BIOQUAL's in vitro laboratory services include: Culturing of permanent cell lines, Isolation of primary cells from blood and tissues, T lymphocyte proliferation assays, Antigen capture assays, ELISAs and Western blots, Cytokine quantitation, Challenge stock development, 6-color flow cytometry services, Immunophenotyping (CD markers), Intracellular cytokine assays, Tetramer/pentamer staining, CFSE labeling, Quantitative real-time PCR for RNA and DNA using the TAQMAN system, Plasmid DNA purification/characterization, Genomic DNA/RNA isolation, Recombinant virus constructions, Transformations/transductions and Antiviral assays for testing of therapeutics.

BIOQUAL's partners include: National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Mach One Corp., The Johns Hopkins University, The US Department of Health and Human Services, Uniformed Services University, and ZooQuest Technologies, Ltd.