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Celsion Corp

10220-L Old Columbia Road
Columbia, MD 21046, USA

Category: Drug Delivery

Used in the following map:

Maryland Biotech Industry Map

Celsion Corp is an oncology drug development company focused on improving treatment for those suffering with highly difficult forms of cancer. The company was founded in 1982 with a vision of using heat to kill cancer and treat other diseases.

Celsion's technology targets localized cancers with high concentrations on chemotherapeutics through the use of its heat activated lipid technology. It develops a liposomal formulation of docetaxel and a number of other liposomal formulations for existing chemotherapeutic cancer drugs. It intends to use various available focused-heat technologies, such as radio frequency ablation ("RFA"), microwave energy and high intensity focused ultrasound, to activate the release of drugs from its novel heat sensitive liposomes. The company has evaluated the liposomal docetaxel formulation in animal studies that demonstrated a statistically significant tumor inhibition effect when compared both to free Docetaxel and a non-heat sensitive formulation. In addition, the company is evaluating in animal studies its heat activated liposomal technology in combination with a peptide ligand that has an affinity for EGF receptors to provide targeted cancer treatments.

Celsion develops a product pipeline of cancer drugs that employ its heat activated liposomal technology. Its products include: ThermoDox plus for the treatment of liver cancer; ThermoDox® for the treatment of recurrent chest wall (RCW) breast cancer; Liposomal carboplatin for the treatment of cancer; and Temperature sensitive liposome with Docetaxel for the treatment of lung cancer.

Celsion's partners include: American Medical Systems Holdings Inc, Boston Scientific Corporation, Duke University, Fast Track Systems, Inc, Koninklijke Philips Electronics N.V, Medidata Solutions, Inc, National Institutes of Health, The U.S. Department of Health and Human Services, Valentis, Yakult Honsha Co., Ltd and so on.