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Clarassance, Inc.

9700 Great Seneca Highway, Suite 314
Rockville, MD 20850, USA

Category: Biotechnology/Biopharmaceutical

Used in the following map:

Maryland Biotech Industry Map

Clarassance, Inc. is specialized in the development of biopharmaceutical products based on the unique family of proteins called secretoglobins. Secretoglobins are small, hardy proteins that are conserved at an evolutionary level. The company was founded by Aprile L. Pilon.

Clarassance's biopharmaceutical product candidate is a recombinant human CC10 protein (CC10), which has several clinical applications in inflammatory, fibrotic, and autoimmune diseases, particularly respiratory diseases. It develops CC10 for respiratory indications including indications in persistent sinusitis, severe influenza-like illness (ILI), and neonatal bronchopulmonary dysplasia. The company's CC10 reduces viral titers for influenza and respiratory syncytial virus.

Clarassance's CC10 is also known as secretoglobin 1A1, CCSP, CC16, uteroglobin, urine protein-1, PCB-binding protein, and blastokinin. Transgenic knockout mice suffer from a number of conditions brought on by a lack of sufficient CC10, including systemic inflammation, poor growth, kidney disease, greater susceptibility to infection, and highly exacerbated responses to respiratory insults such as allergens and ozone.