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Expression Pathology Inc.

9620 Medical Center Drive
Rockville, MD 20850, USA

Category: Bioinformatics/Genomics/Proteomics/Pharmacogenomics

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Expression Pathology Inc. (EPI) is a biotechnology company specializing in the development of innovative tissue protein analysis methods for research and diagnostic applications.

Expression's research and product development is based on two proprietary technologies; tissue dissection using our DIRECTOR laser microdissection slides, and the ability to solubilize FFPE tissue using the patent pending Liquid Tissue MS Protein Prep protocol so the sample can be analyzed using a range of different mass spectroscopy applications. The company offers high level collaborative research and fee-for-service development of tissue protein biomarker assays and comprehensive biomarker discovery and validation. Its services include Tissue Sourcing, DIRECTOR® Slide Laser Microdissection, Liquid Tissue® Sample Processing, Mass Spectrometry Analysis and Bioinformatics Analysis.

Expression has developed internal expertise and proprietary methods that make possible accurate and detailed mass spectrometry analysis of proteins in formalin-fixed paraffin-embedded (FFPE) tissue. Protein analysis in FFPE tissue relies on decades-old immunohistochemistry (IHC). EPI has assembled a patented platform of technologies that work together to enable protein biomarker discovery and accurate measurement of individual proteins and protein pathways in patient tissue that is routinely collected, preserved and stored in medical research and treatment facilities.

Expression Pathology's products include 1) Liquid Tissue® MS Protein Prep Kit - for quantitation and discovery of protein biomarkers in FFPE tissue; 2) DIRECTOR® Laser Microdissection Slides-Direct non-contact microdissection without plastic film or sticky caps; 3) ProteoSOL(TM) Tissue Extraction System.

Expression Pathology has collaboration with The Children's Oncology Group, Roche Holding, Ltd., NextGen Sciences, Inc., Thermo Fisher Scientific Inc., ORIDIS Biomed GmbH, Tom Baker Cancer Centre, Digene Corporation, KPL, Inc. etc.