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Osiris Therapeutics Inc

7015 Albert Einstein Drive
Columbia, MD 21046, USA

Category: Gene/Cell Therapy; Stem Cells

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Maryland Biotech Industry Map

Osiris Therapeutics Inc is a stem cell therapeutic company focused on developing and marketing products to treat medical conditions in the inflammatory, orthopedic, and cardiovascular areas. It was founded in 1992 by Peter Friedli.

Osiris Therapeutics' platform technology uses stem cells which possess anti-inflammatory properties, prevents scar tissue formation and regenerates specific tissue structures, making them potentially useful in a wide range of conditions. The company has developed a first-in-field manufacturing process for the expansion of human mesenchymal stem cells (MSCs). In the manufacturing process, human MSCs are derived from bone marrow aspirate obtained from qualified healthy adult donors. The company is committed to develop its proprietary adult stem cell technology in order to provide physicians with next-generation tools for the treatment and functional restoration of damaged or diseased tissues.

Osiris Therapeutics' stem cell product candidates possess multi-potential character that provides the basis for a cell therapy platform and represents a virtually limitless number of indications. Its product portfolio includes: Prochymal®, a formulation of mesenchymal stem cells (human) indicated for the treatment of several diseases including Acute Graft Versus Host Disease (GvHD), Crohn's Disease, Acute Myocardial Infarction, Acute Radiation Syndrome, etc; and Chondrogen(TM), contains adult human mesenchymal stem cells (hMSCs) indicated for the treatment of osteoarthritis in the knee. The company's biosurgery division harnesses the ability of cells and novel constructs to promote the body's natural healing. Its wound healing products are - Grafix®, a living skin substitute allograft comprised of a biologic membrane with native mesenchymal stem cells used as a covering to promote healing and tissue repair in chronic wounds, limb salvage procedures, tendon repair and burns; and Ovation, an allograft product that provides the necessary elements for tissue repair in an easy-to-use formulation.

Osiris Therapeutics has agreements with Allosource, Genzyme Corporation, Boston Scientific Corporation, Lonza Group Ltd, NuVasive Inc, JCR Pharmaceuticals Co., Ltd, etc.