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Theradigm, Inc.

1448 S. Rolling Road
Baltimore, MD 21227, USA

Category: Gene/Cell Therapy; Stem Cells

Used in the following map:

Maryland Biotech Industry Map

Theradigm, Inc. is engaged in developing cell-based therapies for the treatment of the central nervous system (CNS) disorders.

Theradigm's technology platform is based on Bone Marrow Stromal Cells (BMSC) and Neural Stem Cells (NSCs). It uses BMSCs for treatment of neurological diseases such as cerebral ischemia and spinal cord injury. The company's activities are focused on the establishment of new human NSC lines and development of methods to improve the growth rate and expansion potential of these cells to obtain clinically relevant numbers of these NSCs.

Theradigm's programs address large unmet medical needs in CNS disease, such as stroke, spinal cord injury, ALS (Lou Gehrig's disease) and others. Preclinical data have shown recovery from stroke and traumatic brain injury upon IV infusion of BMSC cells and early preclinical reports with NSCs have demonstrated potential repair in an ALS model as well as homing to brain tumors. Development is underway for an 'off-the-shelf' product for immediate delivery after injury.