US 19 north end, 1936-present
Erie
Common: US 6-6N-120
Erie. US 6 west end (1926-1932); US 6N west end (1932-1936); possible west end US 120 (1926-1928).
US 19 north end, 1932-1936
Erie
US 19 north end, 1926-1932
Erie (possibly ending at the courthouse?)
US 120 west end, 1928-1967
Ridgway
US 120 east end, 1934-1967
Lock Haven
US 120 east end, 1928-1934
Reading
Common: US 422-309-120
Philadelphia. US 120 east end, (1926-1927); US 422 east end (1927-1935); US 309 south end (1930-1935).
US 309 south end, 1926-1930, 1954-1968
Philadelphia
Common: US 309 / US 422
Philadelphia. US 309 south end (1935-1954); US 422 east end (1935-1946)
US 611 south end, 1926-1972
Philadelphia
US 422[E] east end, 1946-1954
Philadelphia
US 422[E] east end, 1954-59; 1961-85
Philadelphia
US 422[E] east end, 1959-1961
Philadelphia
US 422[E] east end, 1985-present
King of Prussia
US 422[E] west end, 1932-1936
Harrisburg
Common: US 15 / US 422
Harrisburg. US 15 north end (1927-1936); US 422[E] west end (1936-1950s)
US 422[E] west end, 1961-present
near Hershey
US 309 north end, 1926-1930
Wilkes-Barre
US 309 north end, 1964-1968
Tunkhannock
US 106 west end, 1926-1973
Wyalusing
US 611 north end, 1926-1929
Scranton
US 611 north end, 1929-1940
Dunmore
US 611 north end, 1940-1954
Scranton
US 611 north end, 1954-1964
Scranton
US 611 north end, 1964-1972
Scranton
Common: US 222 / US 422
Reading: US 222 north end (1926-1932), US 422[E] west end (1927-1932).
US 222 north end, 1932-1954
Allentown
US 222 north end, 1954-1959
Allentown
US 222 north end, 1960s-present
Dorneyville
US 222 north end, 1959-1960s
near Allentown
US 122 south end, 1935-1956
Oxford
US 122 south end, 1956-1963
Morgantown
US 13 north end, 1963-present
Morrisville
US 13 north end, 1926-1963
Morrisville
US 46 west end, 1936-1938(?)
Portland
US 46 west end, 1938(?)-1953
Portland
Common: US 206 / US 209
Milford. US 209 north end (1926-1935); US 206 north end (1934-present... maybe... signage is unclear)
US 206 north end (1960s-present) (maybe)
near Milford (signage is unclear as to whether US 206 ends here or not)
US 209 south end, 1936-present
Millersburg
US 209 south end, 1926-1936
Clarks Ferry
US 230 west end, 1930s-1961
Harrisburg
US 230 west end, 1961-1966
Harrisburg
US 111 north end, 1950s-1961
Harrisburg (west)
US 111 north end, 1961-1963
Harrisburg (east)
US 230 east end, 1926-1954
Lancaster
US 230 east end, 1954-1966
Lancaster
US 422[E] west end, 1950s-1961
Harrisburg
Common: US 15 / US 111
Lawrenceville. US 111 north end (1926-1932); US 15 north end (1936-1939)
US 522 north end, 1949-1977
Selinsgrove
US 522 north end, 1977-present
Selinsgrove
US 522 north end, 1926-1949
Selinsgrove
US 122 north end, 1935-1963
Northumberland
US 140 north end, 1926-1980
Gettysburg
US 322 east end, 1926-1936
Water Street
US 422[W] east end, 1926-1932
Ebensburg
US 422[W] east end, 1932-1961
Ebensburg
US 422[W] east end, 1961-1993
Ebensburg
US 422[W] east end, 1993-present
Ebensburg
US 119 north end, 1926-present
Du Bois
US 224 east end, 1936-1947
New Castle
US 224 east end, 1947-1974
New Castle
US 224 east end, 1933-1936
New Castle
US 224 east end, 1974-1977
New Castle
US 224 east end, 1977-2007
New Castle
US 219 north end, 1926-1934
Bradford
US 111 north end, 1936-1950s
Harrisburg (west)
US 230 west end, 1926-1930s
Harrisburg
US 224 east end, 2007-present
New Castle